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Guide

Who should not take chromium?

Kidney or liver disease, diabetes medication, thyroid hormone replacement and pregnancy or breastfeeding are the situations where chromium needs medical input before starting.

By Electric Tiger Editorial

Chromium isn't right for everyone to start without medical input. People with kidney disease or liver disease, anyone taking insulin or a sulfonylurea for diabetes, anyone on thyroid hormone replacement, and pregnant or breastfeeding people should talk to a doctor first — some of these groups are exactly where the documented risks concentrate.

Kidney or liver disease

Case reports of serious chromium picolinate toxicity — kidney failure and liver dysfunction requiring hospitalization — involved doses well above typical servings, but the kidneys and liver are the organs that clear and process chromium, so anyone with kidney disease or liver disease should ask their doctor before adding a chromium supplement, since reduced clearance changes how a given dose behaves in the body. See chromium side effects for what those case reports described.

Anyone on diabetes medication

The clearest documented effect of chromium is a modest glucose-lowering one in people with diabetes. If you take insulin or a sulfonylurea, that's not a reason to add chromium on your own — talk to your doctor first, because combining a glucose-lowering medication with a supplement that has also been shown to lower glucose can push blood sugar lower than intended. See chromium and medications: what to check.

Anyone taking thyroid hormone replacement

A small controlled study found that taking chromium picolinate together with levothyroxine reduced how much thyroid hormone was absorbed, compared with taking levothyroxine alone. If you take levothyroxine or another thyroid medication, ask your doctor or pharmacist how to space the two apart rather than guessing.

Pregnancy and breastfeeding

Chromium needs shift in pregnancy and lactation, and this page isn't the place to work out a number for either — ask your doctor for guidance specific to your situation rather than using a general adult figure.

Anyone already getting chromium from multiple sources

Chromium shows up in multivitamins, weight-management blends and standalone supplements alike, and it's easy to end up taking more than one product without adding up the total. Since no numeric upper limit has been set, there's no simple ceiling to check a combined total against — see how much chromium should you take a day for what's actually documented at higher, sustained doses, and read the label of every product you take rather than assuming a single serving is the only chromium you're getting.

Questions people ask

Is chromium safe for someone with kidney disease?

Ask a doctor before starting. The kidneys clear chromium, and impaired kidney function changes how a given dose behaves in the body — this is also where the rare serious case reports of chromium toxicity have occurred.

Can people with diabetes take chromium?

Only with a doctor's supervision if they're on insulin or a glucose-lowering medication. Chromium has a documented glucose-lowering effect of its own in people with diabetes, and combining it with medication that does the same thing needs medical oversight, not self-directed dosing.

Who discovered chromium?

The element was identified by French chemist Louis Nicolas Vauquelin in 1797, named for the Greek word for color ("chroma") because of the vivid colors its compounds produce. That's a chemistry-history fact about the element, not about who should or shouldn't take a supplement of it.

Should children take chromium supplements?

This page doesn't cover dosing for children. Talk to a pediatrician before giving any supplement to a child.

Sources

  1. Chromium picolinate toxicity The Annals of pharmacotherapy · 1998 · PMID 9562138A case report describes a woman who developed serious kidney and liver injury after taking 1,200-2,400 mcg/day of chromium picolinate for 4-5 months; she recovered with treatment.
  2. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement The Annals of pharmacotherapy · 2006 · PMID 16492795A case report describes acute kidney injury in a young man after two weeks of a multi-ingredient supplement containing chromium picolinate and several other compounds; he recovered.
  3. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes Journal of clinical pharmacy and therapeutics · 2014 · PMID 24635480
  4. New medications which decrease levothyroxine absorption Thyroid : official journal of the American Thyroid Association · 2007 · PMID 17725434A small controlled study in 7 healthy volunteers found that taking chromium picolinate at the same time as levothyroxine reduced how much thyroid hormone was absorbed, compared with levothyroxine alone.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.