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Research review

Does acai help with diabetes? What the research does and doesn't show

The two placebo-controlled trials that measured blood glucose after weeks of daily acai found no significant difference from placebo. An earlier uncontrolled pilot study reported a glucose difference, but with no comparison group to rule out other explanations.

By Electric Tiger Editorial

The evidence doesn't support acai as a treatment for diabetes or prediabetes. The two placebo-controlled trials that measured blood glucose found no significant difference between acai and placebo. The one trial reporting a glucose improvement had no control group, so nothing rules out other explanations.

What the evidence doesn't support

It doesn't support acai, in any form or dose, as a treatment for diabetes, prediabetes or insulin resistance. It doesn't support using acai in place of a prescribed diabetes medication, or a doctor-directed diet and monitoring plan. And it doesn't support the idea that acai reliably lowers blood glucose — the two placebo-controlled trials that measured it found no significant difference between the acai group and placebo.

What the trials found

A 2011 open-label pilot study gave 10 overweight adults 100 g of acai pulp twice daily (200 g/day) for 30 days, with no control group. Compared with each person's own starting point, fasting glucose and insulin were lower after 30 days (both p<0.02), along with a lower post-meal glucose response. The authors described the results as preliminary and called for a controlled follow-up — without a comparison group, there's no way to separate an acai effect from other explanations, like the diet changes or attention that often come with joining a study.

A 2018 randomized, double-blind, placebo-controlled trial gave 37 adults with metabolic syndrome an acai beverage or placebo, 650 mL/day, for 12 weeks. It found no significant difference between groups on glucose or lipid metabolism markers. It did find lower levels of two inflammation- and oxidative-stress-related markers in the acai group.

A 2020 randomized, double-blind, placebo-controlled trial gave 69 overweight adults with abnormal cholesterol 200 g/day of acai pulp or placebo, added to a reduced-calorie diet, for 60 days. Blood glucose showed no change in either group. The acai group did show lower oxidative-stress and IL-6 markers than placebo.

Across the two placebo-controlled trials — the stronger of the study designs used here — acai made no measurable difference to blood glucose. The one trial that did find a glucose difference had no comparison group at all, so it can't rule out the effect of diet, weight change, or simply retesting a month later.

Questions people ask

Is acai good for diabetes?

The evidence doesn't support that. The best-controlled trials found no effect on blood glucose; the one trial reporting a glucose change had no control group.

Does acai lower blood sugar?

In the two placebo-controlled trials that measured it, no. An earlier, uncontrolled pilot study reported a glucose difference after 30 days, but without a comparison group, that result can't be attributed to acai specifically.

Can I take acai alongside my diabetes medication?

No interaction trial exists for acai and any diabetes medication. Ask your doctor or pharmacist before adding any supplement if you take medication to manage blood sugar.

When to talk to a doctor

A doctor's guidance, ongoing monitoring and, often, medication are how diabetes and prediabetes get handled day to day. Acai is not a treatment for either, and nothing in the trials above supports using it as a substitute for that care. If you have diabetes or prediabetes, or take medication to manage blood sugar, talk to your doctor before adding any supplement.

Sources

  1. Effects of Açai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study Nutrition journal · 2011 · PMID 21569436A 2011 uncontrolled pilot study of 10 overweight adults found several metabolic markers were different after 30 days of high-dose acai pulp compared with their own starting point, but with no control group to rule out other explanations.
  2. Açaí (Euterpe oleracea Mart.) beverage consumption improves biomarkers for inflammation but not glucose- or lipid-metabolism in individuals with metabolic syndrome in a randomized, double-blinded, placebo-controlled clinical trial Food & function · 2018 · PMID 29850709A 2018 placebo-controlled trial in people with metabolic syndrome found no change in glucose or lipid markers after 12 weeks of an acai beverage, but did find lower levels of two inflammation/oxidative-stress markers compared with placebo.
  3. Effects of a hypoenergetic diet associated with açaí (Euterpe oleracea Mart.) pulp consumption on antioxidant status, oxidative stress and inflammatory biomarkers in overweight, dyslipidemic individuals Clinical nutrition (Edinburgh, Scotland) · 2020 · PMID 31307842A 2020 placebo-controlled trial in overweight adults with abnormal cholesterol found lower oxidative-stress and IL-6 markers after 60 days of acai pulp added to a reduced-calorie diet, but no change in cholesterol, triglycerides or blood glucose in either group.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.