Research review
Does beetroot help with inflammation? What the research does and doesn't show
A randomized crossover trial giving older adults with hypertension beetroot juice for 4 weeks found no significant change in C-reactive protein or most inflammatory markers measured, with only a subtle shift in one redox (oxidative-stress) ratio.
The evidence doesn't support beetroot as something that meaningfully reduces inflammation, at least as measured by the standard clinical markers researchers use. A randomized trial giving older adults with hypertension daily beetroot juice for 4 weeks found no significant change in C-reactive protein (CRP), the most commonly used inflammation marker, or in most other inflammatory measures tested — only a subtle shift in one measure of oxidative stress.
What the evidence doesn't support
It doesn't support beetroot lowering CRP, the standard clinical marker doctors use to gauge inflammation — the trial below measured it directly and found no significant change. It doesn't support beetroot as an anti-inflammatory in the way that phrase gets used in marketing, since most of the specific inflammatory markers tested (cytokines, chemokines, adhesion molecules) didn't move either. And we haven't found any human research at all connecting beetroot to gout or uric acid levels specifically — an absence of evidence, not a finding either way.
What the trial found
A randomized, placebo-controlled crossover trial gave 15 men and women (ages 56-71) with hypertension who were on blood pressure medication either nitrate-rich or nitrate-depleted (placebo) beetroot juice, testing both a single dose (about 400 mg of nitrate, measured 3 hours later) and daily intake (twice that amount) for 4 weeks. Researchers measured a wide panel of oxidative-stress and inflammation markers, including hs-CRP, cytokines, chemokines and adhesion molecules. After 4 weeks, CRP and most of the other markers showed no significant difference between the beetroot and placebo conditions. The one measurable change was in a ratio between reduced and oxidized glutathione — a marker of the body's redox balance, not inflammation directly — which shifted modestly toward a less oxidative state with the beetroot juice. The study's own authors described this as a subtle shift, not a clinically meaningful drop in inflammation.
This is a small trial (15 people), in a specific population (older adults with hypertension on blood pressure medication), testing a broad panel of markers rather than one specific inflammatory condition. It's the clearest human evidence we found connecting beetroot to inflammation markers, and on the marker doctors actually use — CRP — it found nothing.
Questions people ask
Is beetroot good for inflammation?
The one trial that measured this directly found no significant change in CRP or most inflammatory markers after 4 weeks of daily beetroot juice. A separate oxidative-stress ratio shifted modestly, which the study authors called subtle, not a meaningful anti-inflammatory effect.
Is beetroot good for gout?
We haven't found human research testing beetroot for gout or uric acid levels. That's an absence of evidence, not a finding that it does or doesn't help.
Is beetroot anti-inflammatory?
The clinical marker most often used to answer that question, CRP, didn't change significantly in the trial above. Marketing language calling beetroot "anti-inflammatory" goes further than what that trial, or any other human trial we found, actually showed.
When to talk to a doctor
Beetroot is not a treatment for gout, arthritis, or any inflammatory condition, and nothing above supports using it as one. If you're dealing with joint pain, swelling, or a diagnosed inflammatory condition, that's a conversation for a doctor rather than something a beetroot supplement addresses.
Sources
- Effects of increased nitrate intake from beetroot juice on blood markers of oxidative stress and inflammation in older adults with hypertension A small randomized crossover trial in older adults with treated hypertension found that daily beetroot juice for 4 weeks did not significantly change C-reactive protein or most inflammatory and oxidative-stress markers measured, with only a subtle shift in one glutathione-based redox ratio.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.