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Research review

Does dandelion root lower cortisol? What the research does and doesn't show

No human trial has tested dandelion root's effect on cortisol or on stress-related weight. The only related research is a two-week mouse study that lowered stress-hormone levels and behavioral signs of despair, without measuring weight at all.

By Electric Tiger Editorial

No human trial has tested whether dandelion root affects cortisol, or whether it does anything to stress-related weight. The only related research is a two-week mouse study: an oral dandelion extract lowered stress-hormone levels and behavioral signs of despair — but it never measured weight, blood sugar, or anything that would answer the "cortisol weight" version of this question.

What the evidence doesn't support

It doesn't support dandelion root, tea, or extract for lowering cortisol in a person, for stress-related weight gain or loss, or as a calming supplement generally. No trial has combined a cortisol measurement with a weight measurement in the same study, in mice or in people — the idea that dandelion root could do both at once hasn't been tested at all.

What the trials found

A 2014 study gave mice an oral water extract of dandelion leaves and roots for 14 days, then put them through two standard rodent stress tests (forced swim and tail suspension). At doses of 50 to 200 mg/kg, the extract shortened immobility time in both tests — a rodent stand-in for reduced behavioral despair, not evidence about mood in a person. Forced-swim stress raised the mice's stress-hormone cascade (CRF, ACTH, corticosterone); 14 days of the extract brought corticosterone down at every dose tested and brought CRF down at the highest dose. The study didn't weigh the mice's body fat or measure blood glucose, so it says nothing about stress-related weight, and the dose was scaled to mouse body weight with no established human equivalent.

A separate line of mouse research has looked at dandelion leaf extract and weight gain on a high-fat diet, but that study didn't measure stress hormones at all — see dandelion root and weight loss: what the research shows for what it actually found. No single study, in animals or people, has tested cortisol and weight together, so nothing supports connecting the two through dandelion root.

What was measured Result in mice Tested in people?
Stress hormones (corticosterone, CRF) Lower after 14 days of extract No
Behavioral despair (forced swim, tail suspension) Less immobility after 14 days No
Body weight or fat Not measured in this study No

Questions people ask

Does dandelion root lower cortisol?

In mice, an oral dandelion extract lowered blood corticosterone (the rodent stress hormone) after two weeks. No human trial has measured cortisol before and after taking dandelion root, so there's no answer for a person yet.

Will dandelion root help with cortisol-related weight gain?

No. No study — animal or human — has measured cortisol and weight in the same dandelion root experiment. The mouse study above didn't track weight at all, and the mouse study that did track weight (linked above) didn't measure cortisol. There's no research connecting the two through dandelion root.

Is dandelion root calming?

The closest evidence is a mouse behavioral test, not a measure of subjective calm in a person. No human trial has given people dandelion root and asked whether they felt calmer.

How much dandelion root should I take for stress?

There's no established dose for stress, because no human trial has tested one. See dandelion root dosage for the doses used in the research that does exist, on other topics.

When to talk to a doctor

Chronic stress that affects sleep, mood, or daily functioning is worth raising with a doctor, and unexplained weight change alongside high stress is worth getting evaluated rather than self-treating. Dandelion root is not a treatment for stress, anxiety, or a cortisol-related condition. If you take medication or are pregnant or nursing, check with a doctor before adding dandelion root; see who shouldn't take dandelion root.

Related reading: dandelion root and weight loss, dandelion root dosage, and what the research shows on dandelion root.

Sources

  1. Antidepressant effects of the water extract from Taraxacum officinale leaves and roots in mice Pharmaceutical biology · 2014 · PMID 24611722In mice, two weeks of an oral dandelion extract reduced behavioral signs of despair in stress-test models and lowered stress-hormone levels (corticosterone, and CRF at the highest dose) after a forced-swim stressor.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.