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Does ginger have digestive enzymes?

Fresh ginger contains a natural protease called zingibain, a genuine digestive enzyme in the same broad category as the protease in a supplement blend. Whether a cup of ginger tea delivers active enzyme is a separate question the lab research doesn't fully answer.

By Electric Tiger Editorial

Yes, fresh ginger root contains a naturally occurring protease enzyme called zingibain, which breaks down protein — the same broad job as the protease in a digestive-enzyme supplement. Whether that enzyme survives being steeped or simmered into tea, though, is a separate question the lab research on it doesn't fully answer.

Ginger's own enzyme, apart from any supplement

Zingibain is a proteolytic enzyme found in raw ginger rhizomes; it's the same enzyme responsible for ginger's traditional use as a meat tenderizer, since it breaks down protein structure on contact. A lab study that purified zingibain from ginger found it a 33.8 kDa protein, most active at 60°C and pH 7.0, and stable for 2 hours across a 40-65°C range. That's a genuine digestive enzyme in the plant itself, separate from anything added by a supplement.

Zingibain isn't one of the five enzymes in DigeZyme (alpha-amylase, neutral protease, lipase, cellulase and lactase). It's a different protease, from a different source, and no trial we've found has tested it for a digestive effect in people the way DigeZyme's blend has been tested for functional dyspepsia.

Does ginger tea have digestive enzymes?

The honest answer is: we don't know how much active zingibain, if any, survives the process of making tea. The lab study above found zingibain stable for 2 hours in a 40-65°C range, but didn't test it at the higher temperatures typically used to steep or simmer ginger tea, or over the shorter brewing time most people actually use. Ginger tea does contain ginger, and ginger contains zingibain in its raw form — but heat generally denatures proteins, including enzymes, and this specific study doesn't tell us where zingibain's activity actually drops off. That's a real gap in what's been tested, not something this page can resolve either way.

Questions people ask

Does ginger tea have digestive enzymes?

Fresh ginger contains a natural protease enzyme (zingibain). Whether it survives active in a brewed cup of tea hasn't been directly tested at typical tea-making temperatures, so we can't say how much, if any, remains functional by the time it's in the cup.

Is zingibain the same as the enzymes in a digestive enzyme supplement?

It's the same broad category — a protease, which breaks down protein — but it's a different specific enzyme from the protease in a blend like DigeZyme, and it hasn't been studied the way DigeZyme's blend has.

Can you take ginger and a digestive enzyme supplement together?

No trial we've found tests that combination. Ginger and a digestive-enzyme supplement are commonly found in the same blend as separate, distinct ingredients, and there's no known mechanism for one to block the other.

Related reading

See what is DigeZyme for what's in a digestive enzyme blend, and ginger tea: how to make it, and what a cup actually provides for how ginger tea compares with the doses used in ginger research generally.

Sources

  1. Evaluation of the Safety and Efficacy of a Multienzyme Complex in Patients with Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study Journal of medicinal food · 2018 · PMID 30156436A 2018 placebo-controlled trial found that adults with functional dyspepsia who took DigeZyme (150 mg/day) for 60 days scored significantly better on several symptom questionnaires than those given a placebo, with no reported product-related side effects; the trial was run and funded by DigeZyme's own maker.
  2. Three phase partitioning of zingibain, a milk-clotting enzyme from Zingiber officinale Roscoe rhizomes International journal of biological macromolecules · 2015 · PMID 25475843A lab study purifying zingibain, ginger's natural protein-digesting enzyme, found it most active at 60°C and stable for 2 hours between 40-65°C; it didn't test the enzyme at the higher temperatures typically used to brew tea.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.