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Research review

Does slippery elm help with GI disease? What the research does and doesn't show

No trial has tested slippery elm alone against GERD, IBS, diverticulitis, ulcerative colitis, Crohn's disease or ulcers. Here's what the small existing research base actually covers.

By Electric Tiger Editorial

The evidence doesn't support slippery elm, taken alone, as a treatment for GERD, IBS, diverticulitis, ulcerative colitis, Crohn's disease or peptic ulcers. No trial has tested it by itself against any of these; the small amount of research that exists combined it with other ingredients in short, uncontrolled studies.

What the evidence doesn't support

It doesn't support slippery elm as a proven treatment for GERD or reflux — the closest evidence is a formula study and a review calling it "popular but under-tested." It doesn't support it for IBS on its own, only inside a multi-herb formula that can't be attributed to slippery elm specifically. And for diverticulitis, ulcerative colitis, Crohn's disease and peptic ulcers, no published human trial identified for this page tested slippery elm, alone or in combination, in people diagnosed with any of them — the absence of research, not a tested negative result.

What the trials found

A 2010 pilot study recruited 31 adults who met Rome II diagnostic criteria for IBS and split them by symptom pattern into two open-label, uncontrolled arms. One formula (bilberry, slippery elm bark, agrimony, cinnamon) was reported to reduce straining, abdominal pain, bloating and flatulence, with a small increase in bowel frequency; the other (slippery elm bark, lactulose, oat bran, licorice root) was reported to increase bowel frequency and improve stool consistency while also reducing straining and bloating. Both were multi-ingredient formulas with no placebo arm, so slippery elm's own contribution can't be isolated.

A 2020 study followed 43 Australian adults with a range of digestive complaints through 16 weeks of a seven-ingredient formula (curcumin, aloe vera, slippery elm, guar gum, pectin, peppermint oil, glutamine), starting at 5 grams a day and increasing to 10 grams a day. Symptoms including heartburn, indigestion, abdominal pain, constipation and diarrhea each fell by roughly 60 to 80 percent on symptom questionnaires, and nearly half of participants taking a reflux medication no longer needed it by the study's end. There was no control group, and seven active ingredients were combined into one formula — the result can't be credited to slippery elm specifically.

A 2019 review of popular remedies for esophageal symptoms — reflux and non-cardiac chest pain — named slippery elm, alongside licorice, peppermint oil and a few others, as popular but under-tested, describing a persistent gap between anecdotal use and controlled research. No trial identified in that review, or found separately for this page, tested slippery elm against a placebo, on its own, for GERD or any other named GI disease.

Named condition What's available
GERD / reflux A multi-ingredient formula study and a review calling slippery elm popular but under-tested; no trial of slippery elm alone
IBS Two multi-herb formulas tested in a diagnosed-IBS sample, open-label, no placebo; no isolated slippery elm result
Diverticulitis No published human trial identified for this page
Ulcerative colitis / Crohn's disease No published human trial identified for this page
Peptic ulcers No published human trial identified for this page

Questions people ask

Is slippery elm good for GERD?

No trial has tested slippery elm alone for GERD. A seven-ingredient formula that included it was linked to large reductions in reflux-type symptoms over 16 weeks in an uncontrolled study, and a separate review called slippery elm a popular but under-tested reflux remedy — neither isolates what slippery elm itself does.

Is slippery elm good for IBS?

The only human research using slippery elm in a diagnosed-IBS sample combined it with two or three other active ingredients in an open-label pilot with no placebo group, so it can't say what slippery elm contributed on its own.

Is slippery elm good for diverticulitis?

No published human trial identified for this page tested slippery elm in people with diverticulitis, during a flare or otherwise.

Is slippery elm good for ulcerative colitis or Crohn's disease?

No published human trial identified for this page tested slippery elm in people diagnosed with either condition.

Is slippery elm good for ulcers?

No published human trial identified for this page tested slippery elm in people diagnosed with a peptic ulcer.

When to talk to a doctor

GERD, IBS, diverticulitis, ulcerative colitis, Crohn's disease and peptic ulcers are all diagnosed conditions that need medical management. Slippery elm is not a treatment for any of them, and nothing above supports using it as a substitute for diagnosis or care from a doctor — especially for new or worsening symptoms, blood in the stool, unexplained weight loss, or a flare of a diagnosed condition.

Related reading: slippery elm benefits: what the research does and doesn't show, slippery elm dosage, and slippery elm side effects.

Sources

  1. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study Journal of alternative and complementary medicine (New York, N.Y.) · 2010 · PMID 20954962A small, uncontrolled pilot study found two multi-herb formulas containing slippery elm bark improved IBS symptoms, but neither formula isolated slippery elm's own contribution.
  2. Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders Nutrition research (New York, N.Y.) · 2020 · PMID 32151878A 16-week uncontrolled study of a seven-ingredient gut-health formula containing slippery elm reported large reductions in GI symptoms, but the formula's other six ingredients make it impossible to credit slippery elm alone.
  3. Popular Remedies for Esophageal Symptoms: a Critical Appraisal Current gastroenterology reports · 2019 · PMID 31289950A 2019 review of popular reflux remedies described slippery elm as popular but under-tested, with a persistent gap between anecdotal use and controlled research.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.