Guide
CoQ10 and magnesium: can you take them together?
No combination study of CoQ10 and magnesium turned up. What is known about each and how to check with a pharmacist.
We found no human study that tested CoQ10 and magnesium together, and none in our sources reporting a problem from combining them. They are different substances: CoQ10 is a compound the body makes, magnesium is a mineral. Whether they can be taken together comes down to your own medicines and conditions, so ask a pharmacist if either applies.
What we looked for, and found
We searched PubMed on 2 October 2026 for trials of CoQ10 combined with magnesium. The results were reviews and trials in people with a medical condition, which we haven't used, and we found none reporting absorption or safety for the pair in healthy adults. We also did not find a sourced reason that they would interfere with each other. That is not proof either way, and it is the full extent of what we can say as research.
What we can cite is each on its own. The CoQ10 safety literature covers ubiquinone at 60 to 1,200 mg a day, with no dose-related stomach complaints (Hathcock 2006; an industry trade body wrote it). CoQ10 is hydrophobic and slowly absorbed (Bhagavan 2006; its authors work for a CoQ10 manufacturer). Magnesium has its own guides: magnesium glycinate dosage and its interactions.
Different things, different jobs
| CoQ10 | Magnesium | |
|---|---|---|
| Type | A compound made in the body; food gives about 3 to 6 mg a day (Pravst 2010) | A mineral |
| Solubility | Fat-soluble | Mineral salts or chelates |
| Dose scale | Tens to hundreds of mg | Elemental mg per serving, stated per form |
| Substitutable? | No | No |
Food data for CoQ10 are from Pravst 2010. Electric Tiger CoQ10 200 mg is 200 mg of coenzyme Q10 as ubiquinone with rice flour in a hypromellose capsule, one capsule a day, as low as $16.31 a bottle on subscription. It contains no magnesium, and we make no benefit claim for it.
Questions people ask
Can you take CoQ10 with magnesium? Can you take them together?
We found no study of the combination and no warning in our sources. Check with a pharmacist if you take prescription medicines, especially blood thinners, which our CoQ10 label names.
Can I take CoQ10 and magnesium glycinate together?
The same answer applies to the glycinate form: no combination study found. Our CoQ10 label directs one capsule a day, 20 to 30 minutes before a meal, and we haven't tested timing against any magnesium product.
What about CoQ10, magnesium and B2 (riboflavin), or red yeast rice and omega-3?
We have not reviewed those combinations. Multi-ingredient products need each ingredient checked at the dose on the label.
CoQ10 vs magnesium: which should I take?
They aren't alternatives. They are different substances, and our sources don't compare them. A decision like that belongs with a clinician.
Do CoQ10 and magnesium have benefits when combined?
We found no trial of the combination to report. What trials of CoQ10 alone found, and the dose gaps, are in the research review.
What else should I check about CoQ10?
Sources
- Risk assessment for coenzyme Q10 (Ubiquinone) A 2006 review of the clinical literature found no dose-related side effects in studies from 60 to 1,200 mg a day.
- Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics A review by authors at a CoQ10 manufacturer reports slow, limited absorption, a peak about 6 hours after a dose and a half-life of about 33 hours.
- Coenzyme Q10 contents in foods and fortification strategies A food-composition review found meat, fish, nuts and some oils richest in CoQ10, with an average dietary intake of only 3-6 mg a day.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
